chan su 蟾酥
Pharmaceutical name: 英文藥名﹕ | Secreto Bufonis |
Botanical name: 學名﹕ | Bufo bufo gargarizans Cantor中華大蟾蜍 Bufo bufo melanostictua Schneider黑 眶蟾蜍 。 |
Pron. in Japanese: 日語發音﹕ | senso |
Pron. in Korean: 韓語發音﹕ | somso |
Pron. in Cantonese: 粵音﹕ | |
Other Names: 別名﹕ | chan su 蟾酥 、cu qiu 促秋、qiu shi 秋施、qiu cu 菊促、ku long 苦龍、he pi 何皮、lai ge ma 癩蛤蟆。 |
Common Name: 英文名﹕ | toad venom |
Distribution: 產地﹕ | Most area in China. Mainly produced in Hebei, Shandong, Sichuan, Hunan, Jiangsu, Zhejiang provinces. 全國大部分地區都有分布,主產於河北、山東、四川、湖南、江蘇、浙江等地。 |
Properties (characteristics)﹕ 性味﹕ | acrid, warm, toxic. 辛,溫。有毒。 |
Channels (meridians) entered:
歸經﹕ | heart, kidney, stomach 腎, 胃,心經。 |
| Medical functions: 藥理﹕
| |
Actions & Indications: 主治﹕ |
4. 用於呼吸、循環衰竭,有迅速而持久的升壓作用,並有顯著的興奮呼吸作用。 |
Chemical ingredients: 化學成份﹕ | 1. steroid type of cardiac stimulant there are more than 10 types, mostly are the product of the drying process of chan su, like cinobufagin, about 5%, resibufogenin RBG, 2. Indole type of alkaloidsbufotenine, bufotenidine, dehydrobufotenine, bufothionine, and serotonin etc. Also contain sterole, epinephrine and different animo acid. 1. 強心甾體化合物為結構類似強心甙而有毒性的蟾毒配基類化合物,已知有10餘種,大多是干燥加 工過程中的分解產物,如華蟾毒配基(又名華蟾毒精cinobufagin)約5%,脂蟾毒 配基(resibufogenin RBG)約3.4%,蟾毒靈約1.8%,羥基華蟾毒基 約1.6%,蟾毒配質 (bufotalin) 約1.5%,遠華蟾毒基 (telocinobufagin) 約1.4%及海 蟾蜍精 (marinobufagin) 等;另含洋地黃毒甙元、沙門甙元等。上述蟾毒配基常在C3與辛二酰精氨酸、庚二酰精氨酸、丁二酰精氨酸、辛二酸、硫酸等結合成酯類,統稱為蟾毒類 ,多存在於加工前 的蟾蜍分泌物中。蟾酥中蟾毒配基和蟾毒的種類及含量,可因原動物、產地、採制時間和方法不同而有差異。 2. 吲哚類生物鹼 主要有蟾酥鹼 (bufotenine) 、蟾酥甲鹼 (bufotenidine) 、去氫蟾酥鹼 (dehydrobufotenine) 、蟾酥硫鹼 (bufothionine) 及5-羥色胺 等。 此外,含有甾醇類、腎上腺素及多種氨基酸。 |
Dosage: 用量﹕ | Use appropriate amount externally or mix with plaster and apply to affected areas. To take orally: 0.015 to 0.03g. (highly toxic). 外用適量,研末調敷或入膏藥內貼患處。內服0.015~0.03g,入丸散。 |
Samples of formulae: 處方舉例﹕ | liu shen wan 六神丸 |
Modern Research: 現代研究﹕ | |
Toxicity & Cautions: 毒素與禁忌﹕ | Not to be taken during pregnancy. In externally application, avoid getting into the eyes. As antidote, make decoction with gan cao 30 g, bai ji 30 g and take orally. 孕婦忌服。外用時注意不可入目。若 中毒時,可用甘 草30克 、白芨片30克煎服解之。 |
蟾酥即蟾蜍耳上腺及皮膚腺 的分泌物。
Last update: Mar 8, 2009; 12:26 p.m. LAH