Pharmaceutical name:

英文藥名﹕

Botanical name:

拉丁生物學名﹕

Lonicera japonica Thunb.

Lonicera confusa (Sweet) DC.  (華南忍冬)

Lonicera hypoglauca Miq. (菰腺忍冬)

Lonicera fuluotomentosa Hsu et S.C.Chneg

Pron. in Japanese:

日語發音﹕

Pron. in Korean:

韓語發音﹕

Pron. in Cantonese::

粵音﹕

Other Names:

別名﹕

Common Name:

英文名﹕

Distribution:

產地﹕

分佈於遼寧、河北、河南、山東、安徽、江蘇、浙江、福建、廣東、廣西、江西、湖南、湖北、四川、貴州、雲南、陝西、甘肅等地。

主產浙江、四川、江蘇、河南、陝西、山東、廣西、湖南等地。此外安徽、甘肅、湖北、江西、福建、山西、雲南、遼寧、河北等地亦產。

Properties

characteristics﹕

性味﹕

甘，寒。

Channels meridians entered:

歸經﹕

心，肺。

藥理﹕

The luteolin of this herb in 1:350,000 concentration can inhibit the growth of Staphylococcus aureus and Bacillus subtilis. Catarrhal bacteria also inhibited Candida albicans, typhoid, dysentery, and Proteus.

The  50% decoction of the above ground part, using the tablet trenching method, can inhibit Salmonella typhi, Shigella flexneri, Staphylococcus aureus and Pseudomonas aeruginosa. T

he 50% juice of the stems and leaves can inhibit  Salmonella typhi, Shigella flexneri and Staphylococcus aureus., but weaker than the  above ground dry parts.

It also possesses strong anti-infection effects in vivo, a strong inhibition effect on Helicobacter  suis.

Anti-inflammatory effect: Dosage of 20mg/kg for 7 days, significantly inhibited  inflammatory process in rats caused by implanted ball of wool .

Cardiovascular role:

luteolin at 5 × 10 concentration, can reduce the magnitude of diastolic function of the isolated frog heart, a slight decrease of the systolic amplitude, heart rate slows down, cardiac output is reduced.

Concentration of 2 × 10, can increase the systolic and diastolic amplitude of the isolated guinea pig heart, fast heart rate, while no direct impact on the coronary artery and blood volume.

Cardiopulmonary devices for dogs: 5-10mg of luteolin can increase the  arterial pressure but reduces venous pressure.

10mg enable lower limb blood flow in rats (33%), 5-15mg can make cats, dogs, blood pressure increased 12 -30%.

The above effects can not be  blocked by alpha-adrenergic blockers.

 0.5g/kg subcutaneous injection in rats enhanced the role of the capillary.

It lowered blood cholesterol in rabbits with experimental artery atherosclerosis.

Anti-spasm: Effects of luteolin:

Reducing spasm effect on the isolated small intestine of the rabbit and  guinea pig tracheal smooth muscle and ileum

Expectorant Effect:

Anti-cancer effects: mouse phenol red method and the test of rat capillary method, luteolin is known as a good anti-cancer effect. Luteolin inhibits the growth of NK / Ly ascites tumor cells in vitro culture.

抗菌作用：本品所含的木犀草素在1：350，000濃度時可抑制葡萄球菌和枯草杆菌的生長。對卡他、白色念珠、傷寒、痢疾、變形等菌亦有抑制作用。

忍冬地上部分50%煎劑，用平板挖溝法，對傷寒杆菌、福氏痢疾杆菌、金黃色葡萄球菌及綠膿杆菌具抑制作用；

莖葉50%鮮汁對傷寒杆菌、福氏痢疾杆菌及金黃色葡萄球菌具抑制作用，但弱於干的整個地上部分。

在體內亦有較強的抗感染作用。對 H. Suis病毒有很強的抑制作用。

消炎作用:在劑量20mg／kg×7d，能明顯抑制大鼠植入羊毛球所致的發炎過程。

對心血管的作用：木犀草素在5×10濃度時，能降低離體蛙心的舒張期幅度，對收縮期幅度有輕度降低，心率變慢，輸出量減少。

在2×10濃度時，能增加離體豚鼠心臟的收縮期及舒張期幅度，心率變快，而對冠狀動脈及血容量則無直接影響。

對狗的心肺裝置，5-10mg木犀草素可使動脈壓有所增加而降低靜脈壓.

10mg可使大鼠下肢血流減少（33%），

5-15mg可使貓、犬血壓升高12-30%。

上述作用不能被α-腎上腺素能阻滯劑所阻斷。

大鼠0.5g／kg皮下注射有增強毛細血管的作用。

對兔實驗性動脈粥樣硬化有降低血膽甾醇的作用。

解痙作用：木犀草素對兔離體小腸、豚鼠氣管平滑肌及回腸有解痙作用。
 

祛痰作用

抗癌作用：用小鼠酚紅法和大鼠毛細管法試驗，木犀草素有較好的抗癌作用。木犀草素對 NK／Ly 腹水癌細胞體外培養有抑制生長的作用。

Actions & Indications:

主治﹕

其功效如金銀花。主要作治療膿腫與潰瘍。

Chemical ingredients:[1]

化學成份﹕[1]

Daly Dosage:

每日用量﹕

External application: use appropriate amount, or boil with water and wash affected areas or grind into powder and apply. Fresh herb can also be pounded and apply to affected areas.

內服：煎湯，10-30 g；或入丸、散；或浸酒。外用：適量，煎水熏洗，或熬膏貼，或研末調敷衍，赤可用鮮品搗敷。

Samples of formulae:

處方舉例﹕

Modern Research:

現代研究﹕

Toxicity & Cautions:

毒素與禁忌﹕

脾虛，泄瀉不止者禁用。