Anti HBV Herbs (in English and Chinese 中英文)
抗乙型肝 炎 病毒之中藥 Click here for mobile users.
by: Joe Hing Kwok Chu 朱興 國編譯
Anti HBV Herbs:[2] | 抗乙型肝 炎病毒之中藥:[2] |
No. | HBV DNA | HBeAg | HBsAg | |||
|---|---|---|---|---|---|---|
Compounds/Extracts ( Herb names) | TI* | Compounds/Extracts ( Herb names) | TI* | Compounds/Extracts ( Herb names) | TI* | |
1 | Chrysophanol 8-O-beta-D-glucoside ( | 270.42 | Ellagic acid (Phyllanthus urinaria) | 13371.43 | Liposome-encapsulated matrine ( | 93.46 |
2 | Artesunate ( Artemisia annua ) 黃花蒿(青蒿)根 | 40 | Water extract ( Hypericum perforatum) 貫葉連翹 | 96.34 | Water extract ( Cynanchum paniculatum) | 80.32 |
3 | Protocatechuic aldehyde ( | 17.27 | Chrysophanol 8-O-beta-D-glucoside ( | 54.52 | Nirtetralin B ( Phyllanthus niruri Linn 珠子草) | 69.63 |
4 | Ethanol extract ( Polygonum cuspidatum, S. et. Z.) 虎杖 | 8.53 | Wogonin ( | 50 | Water extract ( | 66 |
5 | Ethanol extract ( | 7.67 | Water extract ( Mallotus apelta) 白背葉 | 43.08 | Baicalin ( | 65.22 |
6 | Astragaloside IV ( Astragalus) | 7.4 | Water extract ( Mesona procumbens) 仙草 | 34.67 | Aloe emodin ( Rheum tanguticum) 唐古特大黃 | 56.74 |
7 | Matrine ( | 6.39 | Water extract ( Helicteres angustifolia) 山芝麻 | 33 | Wogonin ( | 50 |
8 | Water extract ( Polygonum cuspidatum, S. et. Z.) | 4.76 | Ethanol extract ( | 31.39 | Chrysophanol 8-O-beta-D-glucoside ( | 42.12 |
9 | Wogonin ( | 4.00 | Protocatechuic aldehyde ( | 29.27 | Water extract ( | 38.45 |
10 | 2.98 | Alisol F 24-acetate ( Alisma orientale (Sam.)Juzep.澤 瀉) | 28 | Terpenoids ( Strobilanthes affinis | 36.99 | |
Lamivudine | 30061 | Lamivudine | 1.16 | Lamivudine | 2.53 | |
Herb name | Treatment | No. of ducks | Dosage (mg/kg/day) | Duration (days) | Inhibition rate (%)* | P3 (%)† | References |
|---|---|---|---|---|---|---|---|
Phyllanthus urinaria Guangxiensis 葉下珠 | Extract | 12 | 5000 | 30 | 87.50 | 53.65 | [19] |
Phyllanthus urinaria Yunnanensis | Water extract | 10 | 10000 | 30 | 77.69 | NI | [20] |
Phyllanthus urinaria Guangxiensis | Water extract | 10 | 10000 | 30 | 60.00 | 58.73 | [20] |
Sophora flavescens 苦參 | Liposome-encapsulated matrine | 6 | 20 | 20 | 76.84 | 77.53 | [12] |
Matrine | 6 | 20 | 20 | 42.11 | 33.71 | [12] | |
Rheum palmatum 大黃 | Ethanol extract | 8 | 10000 | 10 | 64.37 | 74.17 | [14] |
Helicteres angustifolia 山芝麻 | Water extract | 10 | 10000 | 14 | 61.95 | 51.00 | [21] |
Water extract | 10 | 10000 | 14 | 33.35 | 25.82 | [22] | |
Scutellaria baicalensis 黃芩 | Wogonin | – | 20 | 10 | >50.00 | >50.00 | [9] |
Salvia miltiorrhiza 丹參 | Protocatechuic aldehyde | 6 | 100 | 10 | 48.40 | 35.90 | [23] |
Artemisia annua 青蒿 （黃花蒿） | Artesunate | 8 | 30 | 28 | 17.51 | NI | [24] |
–, not reported; NI, no inhibition.
*Highest inhibition in plasma DHBV DNA during the treatment.
†Inhibition in plasma DHBV DNA at least 3 days post-treatment withdrawal.
TI: the ratio between CC 50 and IC 50.
*CC 50, IC 50 and references are shown in supplementary materials.
Cytotoxicity is the quality of being toxic to cells. The 50% cytotoxic concentration (CC50)
was defined as the concentration required to reduce the cell number by 50% compared to
that for the untreated controls.
The half maximal inhibitory concentration (IC50) is a measure of the effectiveness of a
substance in inhibiting a specific biological or biochemical function.
Anti carcinoma formula:
Administration of shi quan da bu tang (pronounced as Juzen-taiho-to in Japanese) prevent
hepatocellular carcinoma development.[3]
Anti cirrhosis herb:
bie jia
tao ren
xiao hui xiang
dan shen
xu chang qing ( Cynanchum paniculatum (Bge.) Kitag.)
抗肝硬化之中藥：
鱉甲
桃仁
小茴香
丹參
徐長卿 (一 枝香) 《廣州部隊常用中草藥手冊》
"乙肝大三陽"
濟南中山肝病醫院權威肝病專家介紹說，乙肝大三陽是指在乙肝五項檢查中，
乙肝表面抗原(HBsAg)、
乙肝e抗原(HBeAg)、
乙肝核心抗體(抗 -HBc或HBcAb)
三項指標同時陽性。乙肝大三陽說明患者體內病毒數量較多，病毒復制活躍，
傳染性較強。如果被檢查者的血液檢查為“乙肝大三陽”，但 沒有臨床症狀，
肝功能也正常， 那麼他就不能被稱為乙肝病人，而只能說是乙肝病毒攜帶者
乙肝五項檢查分別是：
表面抗原(HBsAg)
表面抗體(抗HBs)
е抗原(HBeAg)
е抗 體(抗HBe)
核心抗體(抗HBc），
乙肝五項又叫乙肝兩對半。
乙肝小三陽
所謂乙肝“小三陽”是指在乙肝的五 項檢查 (“兩對半”) 檢查的五項指標中，
乙肝表面抗原(HBsAg)、
乙肝E抗體(HBeAb)
乙肝核心抗體(HBcAb)
檢測均是陽性。
豬苓加丹參，豬苓，丹參 對HBV影響：
http://www.cjim.cn/zxyjhcn/zxyjhcn/ch/reader/view_abstract.aspx?file_no=19930913&flag=1
服用十 全大補湯可防止肝癌發生。 [3]
[1] J Viral Hepat. 2013;20(7):445-452.
[2] Zhong Hua Ben Cao 中華本草
[3] Evidence Reports of Kampo Treatment 2010; Task Force for Evidence Reports / Clinical Practice Guideline Special Committee for EBM, the Japan Society for Oriental Medicine