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Herbs that are Not Compatible with Certain Drugs

 by: Joe Hing Kwok Chu

Names of Drugs

Names of Herbs

Reasons:

ampicillin ( Omnipen, Polycillin, Principen)

jia zhu tao夾竹桃
wan nian qing萬年青
fu shou cao福壽草
ampicillin is a strong inhibitor for Psuedomonas Aureginosa. If it use with the cardiac stimulating herb of jia zhu tao, wan nian qiang or fu shou cao it can cause hypokalemia and create cardiac toxicity for the herbs.

Tetracyclines

herbs contain calcium sulfate which may combine with tetracyclines and render it ineffective.

Iron compounds, vitamin B1

the herbs contain large amount of tannin acid and may result in tannin salt

Aluminium Hydroxide , Aminophylline , Sodium Bicarbonate

 

the drugs are alkaline and the herbs are acidic.

Aspirin

 

the herbs posses the effect steroid and aspirin can stimulate the mucus lining of the stomach

corticosteroids
ginseng人參
 possible additive effect

cyclosporine

guan ye lian qiao (St. John's wort)貫葉連翹

 

Digitalis type of drug

 

the herbs contain calcium ions and can increase the toxicity of digitalis and can result in arrhythmia

Digitalis type of drug

 

gan cao甘 草
  

the herb can increase the function of the drug and may cause cardiac exhaustion

Diuretics for expelling potassium

 

gan cao 甘 草
  

the herb has mineralocorticoid effect which can retain sodium and expel potassium and may cause over expelling K and result in low overly potassium.

Erythromycin. (Erythromycinum, Erythrocin, Erythrogran, Robimycin 紅黴素)

Erythromycin can inhibit the function of chuan xin lian in promoting the ability of white cells in killing bacteria.

Sulphonamides

 

 

may cause increase of uric acid crystal formation

Sodim bicarbonate, Aminophylline , theophyline

lowering the effectiveness of the drugs

warfarin, heparin

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

the use of these  herbs may increase the effect of the blood thinning drugs and can cause bleeding. 

phenelzine

induces mania if used  with phenelzine.

serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon

guan ye lian qiao (St. John's wort)貫葉連翹

possible mild serotonin syndrome[2]

indinavir (Crixivan)

guan ye lian qiao (St. John's wort)貫葉連翹

St. John's Wort has been shown to significantly lower indinavir (Crixivan) levels by almost 60%. [1]

interferon

chai hu柴 胡

risk of interstitial pneumonia

atropin, pepsin, and other digestive enzymes

liu shen wan六神 丸
contains arsenic, the main ingredient of xiong huang 雄黃 which is one of the ingredients of liu shen wan. Using it with atropin can cause oxidation of xiong huang and increases the toxicity.

Using liu shen wan with digestive enzyme can lower the effeciveness of the digestive enzyme.

 

indinavir (Crixivan) is a protease-inhibiting drug usually used in combination with other drugs to suppress the replication of HIV.

 

[1] http://www.tthhivclinic.com/stjohnswort.html

[2] 2000 Jan 8;355(9198):134-8.

 

 

 

A manuscript... writing, translating and proofreading  in progress

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Last update: April 16, 2010;  11:50 p.m. LAH

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